The central role of Bcl-3 in atopic dermatitis.
J Invest Dermatol. 2009 Sep;129(9):2088-90
Authors: Massoumi R
Cytokines and hormones are essential mediators in the regulation of antimicrobial peptide and protein (AMP) levels during host defense responses. In this issue, Büchau et al. identify and characterize B-cell leukemia-3 as an important modulator of AMP expression during the innate immune response in keratinocytes as well as in the chronic inflammatory skin disorder atopic dermatitis.
PMID: 19809421 [PubMed - in process]
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